Biosafety data including comparative toxicity, allergencity and feeding studies in experimental animals is generated by companies prior to seeking approval from GEAC as per Rules for the manufacture, use, import, export & storage of hazardous micro organisms, genetically engineered organisms or cells, 1989 and Revised Guidelines for Research in Transgenic Plants & Guidelines for Toxicity and Allergenicity Evaluation of Transgenic Seeds, Plants and Plant parts - 1998.ch in Transgenic Plants & Guidelines for Toxicity and Allergenicity Evaluation of Transgenic Seeds, Plants and Plant parts - 1998.
As of now five genes/events of Bt cotton and one BN Bt cotton variety and NHH Bt cotton hybrid have been approved by GEAC and the biosafety data submitted by the companies is available at following links: