Recombinant Therapeutics being Marketed in India
|
S.No. |
Molecules |
Therapeutic applications |
1 |
Human insulin |
Diabetes |
2 |
Erythropoietin |
Treatment of anaemia |
3 |
Hepatitis B vaccine (recombinant surface antigen based) |
Immunization against Hepatitis B |
4 |
Human growth hormone |
Deficiency of growth hormone in children |
5 |
Interleukin 2 |
Renal cell carcinoma |
6 |
Granulocyte Colony Stimulating Factor |
Chemotherapy induced neutropenia |
7 |
Granulocyte Macrophage Colony Stimulating Factor |
Chemotherapy induced neutropenia |
8 |
Interferon 2Alpha |
Chronic myeloid leukemia |
9 |
Interferon 2Beta |
Chronic myeloid leukemia, Hepatitis B and Hepatitis C |
10 |
Interferons Gamma |
Chronic granulomatous disease and Severe malignant osteopetrosis |
11 |
Streptokinase |
Acute myocardial infarction |
12 |
Tissue Plasminogen Activator |
Acute myocardial infarction |
13 |
Blood factor VIII |
Haemophilia type A |
14 |
Follicle stimulating hormone |
Reproductive disorders |
15 |
Teriparatide (Forteo) |
Osteoporosis |
16 |
Drerecogin (Xigris) alpha |
Severe sepsis |
17 |
Platelet Derived Growth Factor (PDGF) |
Bone marrow induction and osteoblasts proliferation |
18 |
Epidermal Growth factor (EGF) |
Mitogenesis and organ morphogenesis |
19 |
Eptacogalpha (r-F VIIa) r-coagulation factor |
Haemorrhages, congenital or acquired hemophilia |
20 |
Bevacizumab |
Treatment of various cancers, including colorectal, lung and kidney cancer, |
21 |
Trastuzumab |
Treatment of breast cancer |
22 |
Rituximab |
Treatment of many lymphomas, leukemias, transplant rejection and some autoimmune disorders. |
23 |
Darbopoetin alpha |
Treatment of anaemia |
24 |
Human Serum Albumin |
Treatment of liver disease with ascites.
|
25 |
Insulin Glargin |
Treatment of Type I Diabetes Mellitus |
26 |
Insulin Lispro |
Treatment of Diabetes Mellitus |
27 |
Insulin Aspart |
Treatment of Diabetes Mellitus |
28 |
Met-hu-GCSF |
Chemotherapy induced neutropenia |
29 |
Peg-r-metHu-GCSF |
Chemotherapy induced neutropenia |
30 |
Human Interferon alpha 2b |
Treatment of Chronic Hepatitis B |
31 |
Peg-Interferon alpha-2b |
Treatment of Chronic Hepatitis B |
32 |
Human INF beta-1a |
Treatment of multiple sclerosis (MS) |
33 |
Peg Human GCSF |
Chemotherapy induced neutropenia |
34 |
Human PDGF-BB-beta-TCP |
Bone marrow induction and osteoblasts proliferation |
35 |
r-Hu-Chorionic Gonadotropin Hormone |
Role in Pregnancy |
36 |
Hemophilic factor IX |
Treatment of hemophilia |
37 |
Cetuximab |
Treatment of metastatic colorectal cancer and head and neck cancer.
|
38 |
Luteinising Hormone |
Treatment of Reproductive disorders |